Study on dose calculation of low level laser in the treatment of chronic wounds
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https://doi.org/10.54939/1859-1043.j.mst.FEE.2024.135-141Keywords:
Low level laser; Chronic wounds; Therapeutic dose.Abstract
Chronic wounds have failed to progress through a timely repair sequence or one that proceeds through the wound-healing process without restoring anatomic and functional results. Common examples include pressure ulcers, diabetic ulcers, vascular ulcers,... These wounds cause pain and significantly impact patients' health, psychology, and finances, while also placing a burden on healthcare facilities for treatment. Low-level laser therapy has been proven to be an effective method for treating chronic wounds by accelerating the inflammatory phase and stimulating proliferation and healing. However, to meet therapeutic requirements, it is necessary to deliver the correct therapeutic dose (laser energy density). This study establishes a computational model to calculate the absorption and dispersion capabilities of lasers in skin tissue on the back and heel areas with various levels of damage. The purpose is to aid in calculating treatment dosages, enhancing effectiveness, and optimizing the treatment process for chronic wounds.
References
[1]. Bowers, S. and E. Franco, "Chronic wounds: evaluation and management". American family physician. 101(3): p. 159-166, (2020).
[2]. Falcone, M., et al., "Challenges in the management of chronic wound infections". Journal of Global Antimicrobial Resistance. 26: p. 140-147, (2021). DOI: https://doi.org/10.1016/j.jgar.2021.05.010
[3]. Zhang, X., et al., "Functional Biomaterials for Treatment of Chronic Wound". Frontiers in Bioengineering and Biotechnology. 8, (2020). DOI: https://doi.org/10.3389/fbioe.2020.00516
[4]. Kucharzewski, M., et al., "Novel trends in application of stem cells in skin wound healing". European Journal of Pharmacology. 843: p. 307-315, (2019). DOI: https://doi.org/10.1016/j.ejphar.2018.12.012
[5]. Eriksson, E., et al., "Chronic wounds: Treatment consensus". Wound Repair and Regeneration. 30(2): p. 156-171, (2022). DOI: https://doi.org/10.1111/wrr.12994
[6]. Santos, C.M.d., R.B.d. Rocha, F.A. Hazime, and V.S. Cardoso, "A Systematic Review and Meta-Analysis of the Effects of Low-Level Laser Therapy in the Treatment of Diabetic Foot Ulcers". The International Journal of Lower Extremity Wounds. 20(3): p. 198-207, (2020). DOI: https://doi.org/10.1177/1534734620914439
[7]. Stuart, K.B. and C.W. Brian. "To begin at the beginning: The science of bio-stimulation in cells and tissues". in Proc.SPIE. (2006).
[8]. Shirkavand, A., et al., "A new Monte Carlo code for absorption simulation of laser-skin tissue interaction". Chinese Optics Letters. 5(4): p. 238-240, (2007).
[9]. Babak, N., E.M. Thomas, and B. Halil, "Simulation of laser propagation through a three-layer human skin model in the spectral range from 1000 to 1900 nm". Journal of Biomedical Optics. 19(7): p. 075003, (2014). DOI: https://doi.org/10.1117/1.JBO.19.7.075003
[10]. Duyen, T.T.H. and T.A. Tu, "Simulating Low-Level Laser Propagation From Skin Surface To Lumbar Disc, Knee, Femur and Prostate Gland By Monte Carlo Method". Preprints, (2020). DOI: https://doi.org/10.20944/preprints202003.0140.v1
[11]. Black, J., et al., "National Pressure Ulcer Advisory Panel's Updated Pressure Ulcer Staging System". Advances in Skin & Wound Care. 20(5), (2007). DOI: https://doi.org/10.1097/01.ASW.0000269314.23015.e9
[12]. Dominik, M., N.N.A. Rikke, E.E.A. Peter, and K.K.H. Anders, "MCmatlab: an open-source, user-friendly, MATLAB-integrated three-dimensional Monte Carlo light transport solver with heat diffusion and tissue damage". Journal of Biomedical Optics. 23(12): p. 121622, (2018). DOI: https://doi.org/10.1117/1.JBO.23.12.121622
[13]. Shah, P., et al., "Wagner's classification as a tool for treating diabetic foot ulcers: Our observations at a suburban teaching hospital". Cureus. 14(1), (2022). DOI: https://doi.org/10.7759/cureus.21501
[14]. Yu, S., et al., "Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis". Journal of Biomedical Optics. 25(4): p. 045002, (2020). DOI: https://doi.org/10.1117/1.JBO.25.4.045002
[15]. Thưởng, N.V., "Hình ảnh lâm sàng chẩn đoán và điều trị trong chuyên ngành da liễu". Vol. 1: Nhà xuất bản Y học. 769, (2019).
[16]. Thoolen, M., T.J. Ryan, and I. Bristow, "A study of the skin of the sole of the foot using high-frequency ultrasonography and histology". The Foot. 10(1): p. 14-17, (2000). DOI: https://doi.org/10.1054/foot.1999.0568
[17]. Avci, P., et al. "Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring". NIH Public Access, (2013).
[18]. Dam, P.A., et al. "Stimulation of Low-level Laser Light Transmission from the Skin Surface to The Tibia Using The Monte Carlo Method", (2023).
