Developing an application to support cancer diagnosis based on standardized uptake value
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https://doi.org/10.54939/1859-1043.j.mst.89.2023.133-142Keywords:
Positron Emission Tomography combined Computed Tomography (PET/CT); Standardized Uptake Value (SUV); Digital Imaging and Communication in Medicine (DICOM).Abstract
Positron emission tomography (PET) is a type of nuclear medicine procedure that measures the metabolic activity of cells in body tissues that is well suited for detecting, staging and monitoring malignant tumours. The use of PET as a prognostic indicator based on Standardized Uptake Value (SUV) is a powerful tool to supplement the visual interpretation used by physicians. However, when scientists need to conduct desired research, they may face significant difficulties if they have no access to the vendor's application. In this paper, the authors have successfully developed the application based on the algorithm that they proposed. The maximum and average SUV of slices calculated from the authors' application are directly compared with the results from Inobitec DICOM Viewer program and the accuracy is, respectively, 85.4% and 88.7%.
References
[1]. Claude Nahmias, Lindi M. Wahl, “Reproducibility of Standardized Uptake Value Measurements Determined by 18F-FDG PET in Malignant Tumors”, The Journal of Nuclear Medicine, pp. 1804, (2008).
[2]. Paul E. Kinahan, James W. Fletcher, PET/CT Standardized Upatake Values (SUVs) in Clinical Practice and Assesing Response to Therapy”, Seminars in Ultrasound, CT and MRI Vol. 31, Issue 6, pp. 496, (2010). DOI: https://doi.org/10.1053/j.sult.2010.10.001
[3]. Seon-Kyu Kim, Sung Gwe Ahn, Jeong-Yeon Mun, Mi-So Jeong, Soong June Bae, Ju-Seog Lee, Joon Jeong, Sun-Hee Leem, and In-Sun Chu, “Genomic Signature of the Standardized Uptake Value in 18F-Fluorodeoxyglucose Positron Emission Tomography in Breast Cancer”, Cancer Journal, pp. 1-5, (2020).
[4]. Han-Back Shin, Heesoon Sheen, Ho-Young Lee, Jihoon Kang, and Do-Kun Yoon, “Digital Imaging and Communications in Medicine (DICOM) information conversion procedure for SUV calculation of PET scanners with different DICOM header information”, European Journal of Medical Physics, pp. 243-248, (2017). DOI: https://doi.org/10.1016/j.ejmp.2017.05.063
[5]. Somphob Soongsathitanon, Pawitra Masa-Ah. Malulee Tuntawiroon, “A new Standard Uptake Values (SUVS) Calculation based on Pixel Intensity Values”, International Journal of Mathematics and Computers in simulation Volume 6, Issue 1, pp 26-32, (2012). DOI: https://doi.org/10.7748/ns2012.06.26.42.32.p8686
[6]. Sylvain Beaulieu, Paul Kinahan, Jeffrey Tseng, “SUV Varies with Time After Injection in 18F-FDG PET of Breast Cancer: Characterization and Method to Adjust for Time Differences”, The Journal of Nuclear Medicine Volume 44, pp 1044-1049, (2003).
[7]. M. A. Lodge, M. A. Chaudhry and R. L. Wahl, “Noise Considerations for PET Quantification Using Maximum and Peak Standardized Uptake Value”, Journal of Nuclear Medicine, (2012). DOI: https://doi.org/10.2967/jnumed.111.101733
[8]. Claude Nahmias, Lindi M. Wahl, “Reproducibility of Standardized Uptake Value Measurements Determined by 18F-FDG PET in Malignant Tumors”, The Journal of Nuclear Medicine, (2008). DOI: https://doi.org/10.2967/jnumed.108.054239
[9]. Joseph A. Thie, “Understanding the standardzied uptake value, its methods, and implication for usage, Journal of Nuclear Medicine”, 45 (9) 1431-1434, (2004).
[10]. Quantitative Imaging Biomarkers Alliance, Document procedures for computing SUVS from each manufacturer’s images, https://qibawiki.rsna.org/index.php/Standardized_Uptake_Value_(SUV).
