Research on determination of the trinitrotoluene in surface warter by solid-phase extraction with liquid chromatography quadrupole time-of-fly mass (UPLC-MS-QTOF)
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https://doi.org/10.54939/1859-1043.j.mst.VITTEP.2022.107-112Keywords:
Liquid mass chromatography method; Solid-phase extraction; Trinitrotoluene.Abstract
A highly specific and sensitive method for the detection of trinitrotoluene (TNT) using solid-phase extraction (SPE) with optimised Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (UPLC-QToF-MS) procedure has been developed. Two different SPE sorbents, C18 bonded silica (C18 Lichrolut RP-18) and divinylbenzene-N-vinylpyrrolidone (Oasis HLB) were compared. SPE-C18 provided the best results, yielding average recoveries higher than 90%. Detection limits of TNT provided by the proposed SPE-LC-QTOF-MS procedure were 0.21 ng/L.
References
[1]. AOAC International, "How to Meet ISO 17025 Requirements for Method Verification", USA, (2007).
[2]. A.Preiss, A.Bauer, H.-M.Berstermann, S.Gerling, R.Haas, A.Joos, A.Lehmann, L.S, K.S, “Advanced high-performance liquid chromatography method for highly polar nitroaromatic compounds in ground water samples from ammunition waste sites”, Journal of Chromatography A, 1216 (25), pp. 4968-4975 (2009). DOI: https://doi.org/10.1016/j.chroma.2009.04.055
[3]. Becˇanova´, Friedl, Sˇimek, “Identification and determination of trinitrotoluenes and their degradation products using liquid chromatography- electrospray ionization mass spectrometry”, Int J Mass Spectrom, 291, pp. 133-139 (2010). DOI: https://doi.org/10.1016/j.ijms.2010.01.016
[4]. Khuất Hoàng Bình, Nguyễn Thu Hương, Nguyễn Trần Hùng, Hoàng Anh Tuấn, Đinh Thế Dũng, Trần văn Khanh, “Nghiên cứu xác định trinitrotoluen trong nước bằng phương pháp sắc ký lỏng khối phổ (LC-MS/MS)”, Tạp chí Viện Khoa học và công nghệ quân sự, 67 (2020).
[5]. David DeTata, Peter Collins, Allan McKinley, “A fast liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QToF-MS) method for the identification of organic explosives and propellants”, Forensic Science International, 233, pp. 63-74 (2013). DOI: https://doi.org/10.1016/j.forsciint.2013.08.007
[6]. Din En Iso 22478, German Version EN ISO 22478, Beuth, Berlin (2006).
[7]. Method 8330, USEPA, SW-846, “Nitroaromatics, nitramines, and nitrat esters by hight performance liquid chromatography (HPLC)”, US Environmental Protection Agency, Washington, DC (1994).
