Research and development of a kit for the rapid detection of cyanide in water using p-nitrobenzaldehyde and o-dinitrobenzene reagents
199 viewsDOI:
https://doi.org/10.54939/1859-1043.j.mst.88.2023.81-86Keywords:
Cyanide; Blood agents; Toxicity tests; RGB.Abstract
Cyanide is a chemical warfare agent belonging to the group of blood agents. It is a compound capable of destroying cellular oxygen exchange, causing systemic toxicity and rapid death. Many methods have been studied for cyanide detection based on chromogenic reactions, but they often have poor sensitivity, long detection times, and are dangerous due to direct chemical exposure. This paper presents new method for the detection of cyanide in aqueous environment. Under established optimal conditions, cyanide was detected with limit of detection at 50 ppb. Semi-quantitative results of the field samples showed that the method was not effected by factors, capable of detecting cyanide within 15 minutes. In particular, after 30 min, the detection limit can be reached around 2-10 ppb. This method could be applied to detect cyanide in water in the field.
References
[1]. F. R. Sidell et al., “Medical aspects of chemical and biological warfare”, The Surgeon General at TMM Publications, Borden Institute, 721 pages, (1997). DOI: https://doi.org/10.21236/ADA398241
[2]. H. B. Leavesley et al., “Interaction of cyanide and nitric oxide with cytochrome oxidase: implications for acute cyanide toxicity”, Toxicol. Sci., 101 (1), pp. 101-111, (2008). DOI: https://doi.org/10.1093/toxsci/kfm254
[3]. D. M. G. Beasley et al., “Cyanide poisoning: pathophysiology and treatment recommendations”, Occup. Med., 48 (7), pp. 427-431, (1998). DOI: https://doi.org/10.1093/occmed/48.7.427
[4]. M272 Chemical agents water testing kit, NSN 6665-01-134-0885, Luxfer Magtech Inc.
[5]. Bộ phương tiện phân tích K-54, Hướng dẫn sử dụng, NXB Cục Kỹ thuật, (1993).
[6]. Bộ Y tế, QCVN 01-1:2018 về chất lượng nước sạch sử dụng cho mục đích sinh hoạt, 21 trang, (2018).
[7]. TCVN 7723-1:2015 - Chất lượng nước - Xác định cyanide tổng số và cyanide tự do sử dụng trong phương pháp phân tích dòng chảy.
[8]. Siripinyanond A. et al., “A simple cyanide test kit for water and fruit juices”, Anal. Methods, 2, pp. 1698-1701, (2010). DOI: https://doi.org/10.1039/c0ay00458h
[9]. Dangkulwanich M. et al., “A membraneless gas-trapping device for cyanide detection and quantification”, Analytical methods, 12, pp. 2009-2015, (2020). DOI: https://doi.org/10.1039/D0AY00245C
