Green synthesis of MIL-100(Fe) metal-organic frameworks as a carrier for chloroquine delivery

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Authors

  • Le Thanh Bac (Corresponding Author) Institute of Chemistry and Materials, Academy of Military Science and Technology

DOI:

https://doi.org/10.54939/1859-1043.j.mst.76.2021.61-67

Keywords:

MIL-100(Fe); Green process; Ultrasonic; Chloroquine.

Abstract

The metal-organic framework MIL-100(Fe) was synthesized by the green process using the ultrasonic method and water. By using this approach, the energy consumption was reduced by 100 times compared to the hydrothermal method. The prepared MIL-100(Fe) was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and BET surface area measurements. The XRD pattern showed characteristic peaks of MIL-100 (Fe) with the main peaks at 6.3o, 10.3o, 11.1o, and 20.1o. The prepared MIL-100(Fe) was of particle size in a range of from 100 nm to 200 nm, and surface area of 950 m2/g with a pore volume of 0.52 cm3/g. The obtained MIL-100 (Fe) showed a high loading capacity for the chloroquine drug with a maximal capacity of 555 mg/g.

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Published

12-12-2021

How to Cite

Le Thanh Bac. “Green Synthesis of MIL-100(Fe) Metal-Organic Frameworks As a Carrier for Chloroquine Delivery”. Journal of Military Science and Technology, no. 76, Dec. 2021, pp. 61-67, doi:10.54939/1859-1043.j.mst.76.2021.61-67.

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Section

Research Articles