Quality evaluation of synthesized modafinil used as pharmaceutical material
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https://doi.org/10.54939/1859-1043.j.mst.77.2022.98-103Keywords:
Modafinil; Smart drug; Bunte salt; USP.Abstract
Modafinil is a drug used in the treatment of narcolepsy, approved by the FDA in 1998. In previous studies, modafinil was easily synthesized through three stages, in the Bunte salt medium, the overall yield of 74,56 %. The quality of the modafinil was evaluated following USP 41. The results have shown that the synthesized modafinil satisfied quality requirements in pharmacopoeia.
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