Method of rapid detection sulfur mustard in water using 4 - (4 - nitrobenzyl)pyridine as reagent

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Authors

  • Nguyen Minh Tri (Corresponding Author) Institute of New Technology, Academy of Military Science and Technology
  • Vu Ngoc Toan Institute of New Technology, Academy of Military Science and Technology
  • Le Hong Minh Institute of New Technology, Academy of Military Science and Technology
  • Le Ngoc Hoan Faculty of Chemistry, VNU University of Science
  • Nguyen Y Phung Faculty of Chemistry, VNU University of Science

DOI:

https://doi.org/10.54939/1859-1043.j.mst.FEE.2022.207-212

Keywords:

Sulfur mustard; Vesicant chemical warfare agent; Alkylating; SN2. Sulfur mustard; Vesicant chemical warfare agent; Alkylating; SN2.

Abstract

Sulfur mustard (SM) is a vesicant chemical warfare agent. It is a cytotoxic and alkylating compound. Conventional methods of detection of chemical weapons based on chromogenic reactions are waste of time and low sensitivity. This paper presents new method to detect SM in aqueous environment. In the optimal conditions, SM was detected with low limit of detection (LOD), at about 150 ppb. Quantitative results with the help of UV - VIS equipment show that the linear response in the ranges of 150 - 5000 ppb with R2 = 0,9994. This method can be used to develop tests for detection of vesicant agent in the field.

References

[1]. F. R. Sidell et al., “Medical aspects of chemical and biological warfare”, The Surgeon General at TMM Publications, Borden Institute, 721 pages, (1997).

[2]. M. Balali - Mood, B. Balali - Mood, M. Moshiri, “Sulfur mustard”, Encyclopedia of Toxicology (Third Edition), pp. 427 – 431, (2014).

[3]. A. M. Prentiss, “Chemicals in war”, New York, NY, USA, McGraw - Hill Book company Inc, (1937).

[4]. Bộ phương tiện phân tích K - 54, Hướng dẫn sử dụng, NXB Cục Kỹ thuật, (1993).

[5]. A. Bussey, A. Clarke, J. Lambert, “Method for detection mustard”, WO patent 2004081561A1, (2004).

[6]. M. Weber et al., “Determination of warfate agents (nerve agents, blisters agents, saxitoxin and ricin) in food, water and on materials and articles”, Toxichem. Krimtech., Vol. 80, 284, (2013).

[1]. F. R. Sidell et al., “Medical aspects of chemical and biological warfare”, The Surgeon General at TMM Publications, Borden Institute, 721 pages, (1997). DOI: https://doi.org/10.21236/ADA398241

[2]. M. Balali - Mood, B. Balali - Mood, M. Moshiri, “Sulfur mustard”, Encyclopedia of Toxicology (Third Edition), pp. 427 – 431, (2014). DOI: https://doi.org/10.1016/B978-0-12-386454-3.00632-1

[3]. A. M. Prentiss, “Chemicals in war”, New York, NY, USA, McGraw - Hill Book company Inc, (1937).

[4]. Bộ phương tiện phân tích K - 54, Hướng dẫn sử dụng, NXB Cục Kỹ thuật, (1993).

[5]. A. Bussey, A. Clarke, J. Lambert, “Method for detection mustard”, WO patent 2004081561A1, (2004).

[6]. M. Weber et al., “Determination of warfate agents (nerve agents, blisters agents, saxitoxin and ricin) in food, water and on materials and articles”, Toxichem. Krimtech., Vol. 80, 284, (2013).

Published

30-12-2022

How to Cite

Nguyễn Minh Trí, Vũ Ngọc Toán, Lê Hồng Minh, Lê Ngọc Hoan, and Nguyễn Y Phụng. “Method of Rapid Detection Sulfur Mustard in Water Using 4 - (4 - nitrobenzyl)pyridine As Reagent”. Journal of Military Science and Technology, no. FEE, Dec. 2022, pp. 207-12, doi:10.54939/1859-1043.j.mst.FEE.2022.207-212.

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